Our new paper is out!
Published November 29, 2023 17:13
We have moved to a higher level! :)
We have published another communication on flow peptide chemistry. The synthesis of ... Read more
Actual
Design and Characterization of a Multistage Peptide-Based Vaccine Platform to Target Mycobacterium tuberculosis Infection
Published October 18, 2023 13:37
In our recent collaborative article, we ... Read more
Amide isomerization pathways: Electronic and structural background of protonation- and deprotonation-mediated cis-trans interconversions
Published October 18, 2023 12:30
In this article a ... Read more
Covalent fragment mapping of KRasG12C revealed novel chemotypes with in vivo potency
Published October 18, 2023 11:05
We report a covalent fragment screening of our electrophilic fragment library ... Read more
Polymorphic amyloid nanostructures of hormone peptides involved in glucose homeostasis display reversible amyloid formation
Published October 17, 2023 10:58
A group of hormone peptides is stored ... Read more
Inhibitor Design Strategy for Myostatin: Dynamics and Interaction Networks Define the Affinity and Release Mechanisms of the Inhibited Complexes
Published October 16, 2023 10:52
Based on in silico ... Read more
iNext-Discovery in Budapest
Published June 27, 2023 11:07
At the 2023 iNext-Discovery conference, which was situated at Budapest, two of our PhD students presented their research topic. Márton ... Read more
New instrument for peptides production
Published June 08, 2023 21:39
The installation of our second flow peptide synthesizer is ready.
Keep calm and make SPF! :)
A Novel Fusion Protein System for the Production of Nanobodies and the SARS-CoV-2 Spike RBD in a Bacterial System
Published June 03, 2023 10:44
The bacterial expression system presented here ... Read more
Publication award
Published June 01, 2023 10:37
The Institute of Chemistry of the ELTE TTK, the ELTE György Hevesy Doctoral School of Chemistry and the Foundation for Chemical Education have ... Read more
High affinity binding in a flexible protein-protein complex: structural studies on the calmodulin – melittin complex
Published May 23, 2023 16:15
Interaction of calmodulin and melittin is widely ... Read more
Conference participation
Published May 20, 2023 10:18
Several members of our group successfully participated in the KeMoMo-QSAR symposium organized on May 18 in Szeged by the QSAR and Modeling ... Read more
Conference participation
Published May 14, 2023 10:38
Our group successfully participated in the scientific session of the MTA Peptide Chemistry Working Committee held between May 8 and May ... Read more
Scientific and reporting day 2023
Published May 12, 2023 10:19
The doctoral students of our group successfully presented their latest research results in the framework of the 2023 scientific ... Read more
Doctoral title
Published May 11, 2023 19:36
On May 11, Zsolt Dürvanger obtained her doctorate with summa cum laude within the Synthetic Chemistry, Organic and Biomolecular Chemistry program of ... Read more
Covalent fragment mapping of KRasG12C revealed novel chemotypes
Published March 01, 2023 13:21
The G12C mutant KRas is considered druggable by covalent inhibitors. We have screened a covalent ... Read more
Doctoral title
Published February 24, 2023 10:41
On February 23, Anna J. Kiss-Szemán obtained her doctorate with summa cum laude within the Synthetic Chemistry, Organic and Biomolecular Chemistry ... Read more
Succinct Amyloid and Nonamyloid Patterns in Hexapeptides
Published October 03, 2022 11:46
Based on the "Budapest Amyloid Predictor" artificial intelligence program, we determined the most highly ... Read more
The Importance of Mg2+-Free State in Nucleotide Exchange of Oncogenic K-Ras Mutants
Published September 07, 2022 13:28
NMR relaxation data and MD simulations were combined to decipher the role of ... Read more
Approaches to Pyranuronic β-Sugar Amino Acid Building Blocks of Peptidosaccharide Foldamers
Published March 04, 2018 21:26
Pyranuronic β-sugar amino acids (β-SAAs) are biocompatible and tuneable ... Read more