In our recent collaborative article, we described the design and development of an immunogenic, self-adjuvanting, multistage vaccine platform against Mycobacterium tuberculosis (Mtb), obtained by combining the synthesis of a multiepitope...

In this article a possible reaction route for the cis-trans isomerization of non-proline (Xxx-nonPro) peptide bonds is described via protonation using DFT and coupled cluster computational results.

We report a covalent fragment screening of our electrophilic fragment library of diverse non-covalent scaffolds to identify fragments as suitable starting points targeting the Cys12 position of the oncogenic protein KRasG12C.

A group of hormone peptides is stored in the form of functional amyloid fibers in acid secretion vesicles before they reassemble their biologically active helical spatial structure when they enter the blood circulation. In the article published in...

Based on in silico molecular modelling and dynamics simulations, we showed that one of the mutants of the minimum peptide sequences of the GDF11, the 11m2 peptide is a promising inhibitor candidate for the muscle growth regulating myostatin as...