Koltaiandras_cv

András KOLTAI Chemist

Address: https://hu.linkedin.com/in/akoltaia; https://www.facebook.com/akoltaia

Email:

Born In: Budapest

Facility Manager: Dr. András Perczel

Studies

2013-2015: MSc. student in chemistry, Eötvös University (ELTE), Budapest; degree with honours; National scientifical student conference (XXXII. OTDK Kémiai és Vegyipari Szekció) 2015. first prize; scholarship of the republic (Köztársasági Ösztöndíj) 2014/15; excellent student of the faculty award (Kar Kiváló Hallgatója díj) 2014; scientifical student conference of the Institute of Chemistry (Kari Kémiai Tudományos Diákköri Konferencia); 2013, jury's grand first prize

2010-2013: BSc. student in chemistry, Eötvös University (ELTE), Budapest, degree with honours

2006-2010: High-school of Piarists, Budapest

Research experiences

06/2014–06/2015 Professional internship at Chinoin Zrt. - a Sanofi company
Budapest (Hungary)
Supervisor: Dr. Péter HUDÁKY, development analyst; and Dr. Miklós MORVAI, head of Chemical Analitical Development
Guided analytical work at Chemical and Biotechnological Process Development
- qualitative and quantitative NMR study of commercial, laboratory, pilot plant and industrial samples
- qualitative and quantitative study of contaminantions
- definition of known and new structures of chemicals based on NMR and HPLC-MS measurements
- NMR measurements and data processing (Bruker Avance III, 500 MHz, Topspin)
- HPLC-MS measurements and data processing (Acquity UPLC system + Micromass QTOF Premier, and Agilent HPLC system + Thermo Scientific TSQ Quantum)
- documentation in Hungarian and in English
Acquired skills
- analytical view
- confident skills in preparing samples and NMR measurement of small molecules, individual skills in planning experiments
- confident skills in manipulation with NMR spectra of small molecules (<=600 Da), data processing, assignation, elucidation of structure
- complex NMR-MS problem-solving skills
- basic HPLC-MS and UPLC-MS knowledge
- confident documentation skills in Hungarian and basic documentation skills in English
- industrial view, experience in production supporting analytics
- (about 500 man-hours) experience in industrial enviroment, in applied R&D

04/2012–04/2015 Professional internship at ELTE Laboratory of Structural Chemistry and Biology
Budapest (Hungary)
Supervisor: Professor András PERCZEL, academist
Guided research
- structural study of miniproteins, based on 2D homo-, and heteronuclear NMR spectra (e.g. COSY, TOCSY, NOESY, 13C HSQC, 15N HSQC)
- dynamic study of miniproteins, based on 2D and 3D heteronuclear NMR spectra; using T1 and T2 relaxation, hetNOE, Lipari-Szabó formalism and CPMG measurements
- DOSY measurements of miniproteins
- qualitative and quantitative 19F NMR and 31P NMR studies
- studies of reaction kinetics based on 1H and 31P NMR detection
- NMR measurements on 250 MHz and 700 MHz (Bruker Topspin 2.0-3.2); 1D and 2D homo-, and heteronuclear measurements
- frequent filling of NMR instruments with liquid nitrogen
Acquired skills
- confident user-level NMR knowledge in measurement and data processing
- basic maintenance knowledge of NMR instruments
- confident skills in preparing BioNMR samples (in NMR tube or in Shigemi microtube)
- confident skills in structural and dynamical NMR study of proteins and peptides
- confident skills in DOSY measurement and data processing
- confident skills in planning of analytical studies, processing and concluding its data
- confident skills in individual work and in teamwork
- confident, individual documentation and presentation skills in Hungarian
- 3 years (about 2 500 man-hours) of experience in academic enviroment and basic research

08/2011–03/2012 Professional internship at ELTE Department of Inorganic Chemistry
Budapest (Hungary)
Supervisor: Dr. Antal CSÁMPAI, associate professor
Guided synthetic research
- synthesis of new ferrocene-based heterocycles
Acquired skills
- confident skills in organic and organometallic synthesis
- basic skills in work at inert atmosphere
- basic skills in separation and purification of compounds with classical (non instrumental) methods

Publications

TDK presentations

  • XXXII. OTDK Kémiai és Vegyipari Szekció, Veszprém, 2015. április 10.
  • Kari Kémiai Tudományos Diákköri Konferencia, Budapest, November 22, 2014
  • Kari Kémiai Tudományos Diákköri Konferencia, Budapest, December 7, 2013
  • Biológus Tudományos Diákköri Konferencia, Budapest, November 13, 2013

Presentations

  • Magyar NMR Munkabizottság, 2015. tavaszi munkabizottsági ülés, Balatonszemes, 2015. április 24-25.
  • Magyar NMR Munkabizottság, 2014. őszi munkabizottsági ülés, Balatonszemes, 2014. október 2-3.
  • XXXVII. Kémiai Előadói Napok, Szeged, 2014. november 3-5.
  • Peptidkémiai Munkabizottság tudományos ülése, Balatonszemes, 2014. május 28-30.
  • XIX. Bolyai Konferencia, Budapest, 2014. március 22-23.
  • XXXVI. Kémiai Előadói Napok, Szeged, 2013. október 28-30.

Posters

  • Structure and dynamics of SS-bond stabilized miniproteins (The 6th Central European Conference “Chemistry towards Biology”, Trieste, Italy, September 10-13, 2013)
  • Versatile Researches on Chiral Ferrocenes (10th Ferrocene Colloquium, Braunschweig, Germany, February 15-17, 2012)

Awards

- national scientifical student conference (XXXII. OTDK Kémiai és Vegyipari Szekció) 2015. first prize

- scholarship of the republic (Köztársasági Ösztöndíj) 2014/15

- excellent student of the faculty award (Kar Kiváló Hallgatója díj) 2014

- scientifical student conference of the Development of Chemistry (Kari Kémiai Tudományos Diákköri Konferencia), 2013, jury's grand first prize