in spectra

NMR, ECD,

VCD, FTIR,..

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in crystal

 X-ray diffraction,

crystallography,...

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in silico

bio-informatics, applied QM,

molecular modeling,...

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in vivo/in vitro

biotechnology, protein production, 

preparative work, classical synthesis,..

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Using both classical organic chemistry and modern bacterial expression systems we synthesize polypeptides, foldamers and proteins of various size and biological significance. Structure elucidation and internal dynamics of biomolecules are completed by X-ray and bioNMR spectroscopy, as well as molecular modeling, applied quantum chemistry and bioinformatics. We do cooperate with both Hungarian and foreign research teams on subjects ranging from organic chemistry to molecular biology. Recently we are synthesizing amino acids derived form carbohydrates, determining conformational properties of beta amino acids, synthesizing foldamers, expressing Exenatide-4 analogs used to treat type II Diabetes Mellitus, and conducting research for a better understanding Alzheimer’s and other conformational diseases, etc…Devoted students and people interested in modern structural chemistry and biology are always welcome. P1030653

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