We do cooperate with both Hungarian and foreign research teams on subjects ranging from organic chemistry to molecular biology. We run several ELTE-based, joint research projects, even at the national level, such as MedInProt, HunProtExc, or the SynthPlusz Excellence Programs. Recently we are synthesizing amino acids derived from carbohydrates, determining conformational properties of beta amino acids, synthesizing foldamers, expressing Exenatide-4 analogs used to treat type II Diabetes Mellitus, and conducting research for a better understanding Alzheimer’s and other conformational diseases. Furthermore, we work on the structure and dynamics of kRas signaling protein, which plays an important role in tumor diseases. Devoted students, postdocs and researchers interestedin modern structural chemistry and biology.
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Recent Publications
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Viktória Goldschmidt Gőz , Kim Hoang Yen Duong , Dániel Horváth , Kristóf Ferentzi , Viktor Farkas , András Perczel
Application of Sugar Amino Acids: Flow chemistry used for α/β-chimera synthesis
Eur. J. Org. Chem. 6071–6083. | In memory of Ferenc Fülöp | doi: https://doi.org/10.1002/ejoc.202100943 (2021) Kivonat -
Laura Bereczki , Lara Alexandre Fogaça , Zsolt Dürvanger , Veronika Harmat , Katalin Kamarás , Gergely Németh , Berta Barta Holló , Vladimir M. Petruševski , Eszter Bódis , Attila Farkas , Imre Miklós Szilágyi , László Kótai
Dynamic disorder in the high-temperature polymorph of bis[diamminesilver(I)] sulfate-reasons and consequences of simultaneous ammonia release from two different polymorphs
Journal of Coordination Chemistry 74:13, 2144-2162 | DOI: 10.1080/00958972.2021.1953489 (2021) Kivonat -
László Keresztes , Evelin Szögi , Bálint Varga , Viktor Farkas , András Perczel , Vince Grolmusz
The Budapest Amyloid Predictor and Its Applications
Biomolecules 11(4), 500 | DOI: 10.3390/biom11040500 (2021) Kivonat -
István Vida , Zsolt Fazekas , Gegő Gyulai , Dóra Nagy-Fazekas , Pál Stráner , Éva Kiss , András Perczel , Gyula Pálfy
Bacterial fermentation and isotope labelling optimized for amyloidogenic proteins
Microbial Biotechnology 14, 1107–1119. | https://doi.org/10.1111/1751-7915.13778 (2021) Kivonat -
Duong Kim Hoang Yen , Viktória Goldschmidt Gőz , András Perczel , István Pintér
Synthesis of chimera oligopeptide including furanoid ß-sugar amino acid derivatives with free OHs: mild but successful removal of the 1,2-O-isopropylidene from the building block
Amino Acids 53: 281–294 | DOI: 10.1007/s00726-020-02923-3 (2021) Kivonat - More publications