Using both classical organic chemistry and modern bacterial expression systems we synthesize polypeptides, foldamers and proteins of various size and biological significance. Structure elucidation and internal dynamics of biomolecules are completed by X-ray and bioNMR spectroscopy, as well as molecular modeling, applied quantum chemistry and bioinformatics. We do cooperate with both Hungarian and foreign research teams on subjects ranging from organic chemistry to molecular biology. Recently we are synthesizing amino acids derived form carbohydrates, determining conformational properties of beta amino acids, synthesizing foldamers, expressing Exenatide-4 analogs used to treat type II Diabetes Mellitus, and conducting research for a better understanding Alzheimer’s and other conformational diseases, etc…Devoted students and people interested in modern structural chemistry and biology are always welcome. 
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Recent Publications
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László Keresztes , Evelin Szögi , Bálint Varga , Viktor Farkas , András Perczel , Vince Grolmusz
The Budapest Amyloid Predictor and Its Applications
Biomolecules 11(4), 500 | DOI: 10.3390/biom11040500 (2021) Kivonat -
István Vida , Zsolt Fazekas , Gegő Gyulai , Dóra Nagy-Fazekas , Pál Stráner , Éva Kiss , András Perczel , Gyula Pálfy
Bacterial fermentation and isotope labelling optimized for amyloidogenic proteins
Microbial Biotechnology https://doi.org/10.1111/1751-7915.13778 (2021) Kivonat -
Duong Kim Hoang Yen , Viktória Goldschmidt Gőz , András Perczel , István Pintér
Synthesis of chimera oligopeptide including furanoid ß-sugar amino acid derivatives with free OHs: mild but successful removal of the 1,2-O-isopropylidene from the building block
Amino Acids 53: 281–294 | DOI: 10.1007/s00726-020-02923-3 (2021) Kivonat -
Viktor Farkas , Kristóf Ferentzi , Kata Horváti , András Perczel
Cost Effective Flow Peptide Synthesis: Metamorphosis of HPLC
Organic Process Research & Development 25(2): 182-191 | doi: 10.1021/acs.oprd.0c00178 (2021) Kivonat -
Andrea Bodor
Intrinsic structural disorder of proteins: from prediction to experimental identification
Amino Acids, Peptides and Proteins https://doi.org/10.1039/9781788017008-00064 (2020) Kivonat - More publications