Dr. Gyula Pálfy research fellow
Address: 1/A, Pázmány Péter sétány, Budapest, Hungary, H-1117
Room: 301.
Email:
Phone: +36 (1) 372-2500 / 6422
Facility Manager: Dr. Andrea Bodor
Studies
2003-2007: Fazekas Mihaly Secondary School of Budapest
2007-2010: Eotvos Lorand University (Budapest/Hungary), Chemistry B.Sc.
2010-2013: Eotvos Lorand University (Budapest/Hungary), Chemist M.Sc.
(in between Erasmus student at University of Leeds, UK)
2011-2018: Szent Pal Academy, theology MA
2013-2019: Eotvos Lorand University (Budapest/Hungary), Chemistry PhD
Posts Held
2010 – 2013: president of JÖVŐKÉPP – Youth for Hungary! Association
2010 – 2012: representative of Eotvos Lorand University Student Union, member of Science Group
2010 – 2012: student member of Council of Eotvos Lorand University Institute of Chemistry
Publications
Prime Publications
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Gyula Pálfy , Bence Kiss , László Nyitray , Andrea Bodor
Multi-level changes in protein dynamics upon complex formation of the calcium-loaded S100A4 with a non-muscle myosin IIA tail fragment
ChemBioChem 17(19):1829-1838 DOI: 10.1002/cbic.201600280 | PMID: 27418229 (2016) Kivonat -
Beáta Biri-Kovács , Bence Kiss , Henrietta Vadászi , Gergő Gógl , Gyula Pálfy , György Török , László Homolya , Andrea Bodor , László Nyitray
Ezrin interacts with S100A4 via both its N- and C-terminal domains
PLoS One 12(5):e0177489 | doi: 10.1371/journal.pone.0177489 | PMID: 28493957 (2017) Kivonat -
Péter Ecsédi , Neil Billington , Gyula Pálfy , László Nyitray , Bence Kiss , Éva Bulyáki , Andrea Bodor , James R. Sellers
Multiple S100 protein isoforms and C-terminal phosphorylation contribute to the paralog-selective regulation of nonmuscle myosin 2 filaments
The Journal of Biological Chemistry 293(38) 14850 –14867. | DOI10.1074/jbc.RA118.004277 (2018) Kivonat -
Moira Rachman , Andrea Scarpino , Dávid Bajusz , Gyula Pálfy , István Vida , András Perczel , Xavier Barril , György M. Keserű
DUckCov: a Dynamic Undocking-Based Virtual Screening Protocol for Covalent Binders
ChemMedChem 14, 1 – 12 DOI: 10.1002/cmdc.201900078 (2019) Kivonat -
Gyula Pálfy , István Vida , András Perczel
1H, 15N backbone assignment and comparative analysis of the wild type and G12C, G12D, G12V mutants of K‐Ras bound to GDP at physiological pH
Biomolecular NMR Assignments 14, 1-7 | doi.org/10.1007/s12104-019-09909-7 (2020) Kivonat -
Kinga Nyíri , Gergely Koppány , Gyula Pálfy , István Vida , Szilárd Tóth , Zoltán Orgován , Ivan Ranđelović , Marcell Baranyi , Eszter Molnár , György M. Keserű , József Tóvári , András Perczel , Beáta G. Vértessy , József Tímár
Allélspecifikus inhibitorok nyomában: a RASopátia konzorcium célpontjában a KRAS fehérje onkogén mutációi
Magyar Onkológia 63(4), 310-323 (2019) Kivonat -
Erika F. Dudás , Gyula Pálfy , Dóra K. Menyhárd , Fanni Sebák , Péter Ecsédi , László Nyitray , Andrea Bodor
Tumor‐Suppressor p53TAD1–60 Forms a Fuzzy Complex with Metastasis‐Associated S100A4: Structural Insights and Dynamics by an NMR/MD Approach
ChemBioChem 21 | doi.org/10.1002/cbic.202000348 (2020) Kivonat -
Gyula Pálfy , Dóra K. Menyhárd , András Perczel
Dynamically encoded reactivity of Ras enzymes: opening new frontiers for drug discovery
Cancer and Metastasis Reviews doi.org/10.1007/s10555-020-09917-3 (2024) Kivonat -
Dóra K. Menyhárd , Gyula Pálfy , Zoltán Orgován , István Vida , György M. Keserű , András Perczel
Structural impact of GTP binding on downstream KRAS signaling
Chemical Science DOI: 10.1039/d0sc03441j (2020) Kivonat