Dsc_5309

Fanni Sebák

Address: 1117 Budapest, Pázmány Péter sétány 1/a

Room: 4.103

Email:

Phone: +36 (1) 372-2500 / 6422

Born In: Esztergom

Facility Manager: Dr. Andrea Bodor

Lab: NMR lab.

Studies

2011-2016: Pharmacist M.Sc., Semmelweis University, Budapest 

2016-        : Doctoral School of Pharmaceutical Sciences, Semmelweis University, Budapest

Teaching experiences

Teaching in Hungarian

2017- : Instrumental Analysis Laboratory Practice – ¹H and ³¹P NMR, PFG-NMR
2017- : Analytical Chemistry (qualitative) Practice (Semmelweis University, Faculty of Pharmacy)
2016-2017: Analytical Chemistry (quantitative) I-II. Practice (Semmelweis University, Faculty of Pharmacy)

Teaching in English

2018: General and Inorganic Chemistry I. Practice  (Semmelweis University, Faculty of Pharmacy)

Teaching in German

2019: General and Inorganic Chemistry I. Practice (Semmelweis University, Faculty of Pharmacy)
2019-2020: Analytical Chemistry (qualitative) Practice (Semmelweis University, Faculty of Pharmacy)

Research

Structural characterization of folded and disordered proteins using solution state NMR methods

Peptide-membrane mimetics interactions

Publications

MTMT ID: 10059303

ORCID ID: 0000-0001-9252-9961

ResearcherID: E-6943-2017

Presentations

Sebák, F.; Bermel, W.; Nyitray, L.; Luy, B.; Bodor, A.: Functionally important Pro conformations in proteins: how to determine them?; Hungarian NMR Discussion Group, Balatonszemes, 17.05.2019

Sebák, F.; Dudás, E. F.; Pálfy, Gy.; Ecsédi, P.; Menyhárd, D. K.; Nyitray, L.; Bodor, A.: The importance of proline conformation in the TAD domain of p53 in free form and in fuzzy complex with S100A4; Chemistry towards Biology (CTB9) Conference, Budapest, 24-27.09.2018

Sebák, F.; Boros, E.; Pál, G.; Bodor, A.: A hurokcsere hatásának vizsgálata kanonikus szerin proteáz inhibitorok esetében; Hungarian NMR Discussion Group, Balatonszemes, 24-25.05.2018

Sebák, F.; Boros, E.; Pál, G.; Bodor, A: Role and structure of scaffolds in canonical serine protease inhibitor variants: an NMR spectroscopic view; PhD Scientific Days, Semmelweis University, Budapest, 19-20.04.2018.

Posters

Sebák, F.; Wacha, A.; Novák, L.; Bányai, I.; Bóta, A.; Bodor, A.: Bicelle-Peptide Interactions: Combined NMR-SAXS Approach to Characterize Global and Local Parameters; ENC Virtual Conference; 29-31.03.2021

Sebák, F.; Wacha, A.; Bóta, A.; Bodor, A.: Characterizing Bicelle Size Using a Combined NMR-SAXS Method; EUROMAR on-line meeting, 7-8. 12.2020.

Sebák, F.; Dudás, E. F.; Wacha, A.; Bóta, A.; Bodor, A.: Global and local parameters to characterize peptide-membrane mimetics interaction; EUROISMAR 2019 Conference, Berlin, Germany, 25-30.08. 2019.

Sebák, F.; Dudás, E. F.; Pálfy, Gy.; Ecsédi, P.; Menyhárd, D. K.; Nyitray, L.; Bodor,: Structural characterization of the minor form of p53 transactivation domain; iNEXT Structural biology approaches for drug development, Budapest, 27-29.09.2018.

Sebák, F.; Dudás, E. F.; Nyitray, L.; Bodor, A.: Proline conformation in the TAD domain of p53; EUROMAR 2018 Conference, Nantes, France, 01-05.07.2018

Prime Publications

  • Eszter Boros , Fanni Sebák , Dávid Héja , Dávid Szakács , Katalin Zboray , Gitta Schlosser , András Micsonai , József Kardos , Andrea Bodor , Gábor Pál
    Directed Evolution of Canonical Loops and Their Swapping between Unrelated Serine Proteinase Inhibitors Disprove the Interscaffolding Additivity Model
    J. Mol. Biol. 431, 557–575 | doi.org/10.1016/j.jmb.2018.12.003 (2019) Kivonat
  • Erika F. Dudás , Gyula Pálfy , Dóra K. Menyhárd , Fanni Sebák , Péter Ecsédi , László Nyitray , Andrea Bodor
    Tumor‐Suppressor p53TAD1–60 Forms a Fuzzy Complex with Metastasis‐Associated S100A4: Structural Insights and Dynamics by an NMR/MD Approach
    ChemBioChem 21 | doi.org/10.1002/cbic.202000348 (2020) Kivonat
  • Maria Ricci , Kata Horváti , Tünde Juhász , Imola Szigyártó , György Török , Fanni Sebák , Andrea Bodor , László Homolya , Judit Henczkó , Bernadett Pályi , Tamás Mlinkó , Judith Mihály , Bilal Nizami , Zihuayuan Yang , Fengming Lin , Xiaolin Lu , Loránd Románszki , Attila Bóta , Zoltán Varga , Szilvia Bõsze , Ferenc Zsila , Tamás Beke-Somfai
    Anionic food color tartrazine enhances antibacterial efficacy of histatin-derived peptide DHVAR4 by fine-tuning its membrane activity
    Quarterly Reviews of Biophysics 53(5), 1-11 | DOI: 10.1017/S0033583520000013 (2020) Kivonat

List of Publications

Awards

Suraj Manrao Student Poster Prize, EUROMAR 2018 Conference, Nantes, France

Fellowship

Predoctoral Fellowship, Semmelweis University (EFOP-3.6.3-VEKOP-16-2017-00009)

Fellowship of the Foundation for the Hungarian Peptide and Protein Research