Aggregation of Elongated Trp-Cage Proteins

Published June 15, 2013 18:54

In this article (EuJOC) we present the aggregation propensity of 3 Trp-cage foldamers: E0 (20 aa), E5 (25 aa) and E10 (30 aa) models of different sizes but comparable molecular folding properties. ECD, VCD and FT-IR spectroscopies were used to monitor their concentration-dependent, heat-induced (5 -> 65 °C) “α to β” fold transitions.

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