Zsolt Fazekas PhD student

Room: 427/A

Email:

Born At: October 29, 1994

Born In: Budapest

Facility Manager: Dr. András Perczel

Studies

2005-2013: Jedlik Ányos Secondary School, Budapest
2013-2016. Eötvös Loránd University, Budapest, Hungary - Chemistry BSc
2016-2018. Eötvös Loránd University, Budapest, Hungary - Chemistry MSc (Pharmaceutical Research, Synthetic Chemistry specializations)
2018-. Eötvös Loránd University, Budapest, Hungary - Hevesy Chemistry Doctoral School (Synthetic Chemistry, Material Science and Biomolecular Chemistry)

Teaching experiences

2018-2019/I. General Chemistry Practical Course (Biology BSc, 4x3 hours of laboratory practise and 4x1,5 hours of normal course, course code: altkemk17la)

Research

Recombinant protein expression in flask and fermenter (bioreactor) systems, their isotope labelling and NMR spectroscopic investigation.

Publications

Prime Publications

Zsolt Fazekas , Dóra K. Menyhárd , András Perczel
LoCoHD: a metric for comparing local environments of proteins
Nature Communications 15, 4029 I DOI: https://doi.org/10.1038/s41467-024-48225-0 (2024) Kivonat
Zsolt Fazekas , Dóra K. Menyhárd , András Perczel
Omicron Binding Mode: Contact Analysis and Dynamics of the Omicron Receptor-Binding Domain in Complex with ACE2
Journal of Chemical Information and Modelling DOI: 10.1021/acs.jcim.2c00397 (2022) Kivonat
Márton Gadanecz , Zsolt Fazekas , Gyula Pálfy , Dóra Karancsiné Menyhárd , András Perczel
NMR-Chemical-Shift-Driven Protocol Reveals the Cofactor-Bound, Complete Structure of Dynamic Intermediates of the Catalytic Cycle of Oncogenic KRAS G12C Protein and the Significance of the Mg2+ Ion
Int. J. Mol. Sci. 24(15), 12101 I https://doi.org/10.3390/ijms241512101 (2023) Kivonat
Dóra Nagy-Fazekas , Zsolt Fazekas , Nóra Taricska , Pál Stráner , Dóra Karancsiné Menyhárd , András Perczel
Inhibitor Design Strategy for Myostatin: Dynamics and Interaction Networks Define the Affinity and Release Mechanisms of the Inhibited Complexes
Molecules 28(15), 5655 | https://doi.org/10.3390/molecules28155655 (2023) Kivonat
István Vida , Zsolt Fazekas , Gergő Gyulai , Dóra Nagy-Fazekas , Gyula Pálfy , Pál Stráner , Éva Kiss , András Perczel
Bacterial fermentation and isotope labelling optimized for amyloidogenic proteins
Microbial Biotechnology 14, 1107–1119. | https://doi.org/10.1111/1751-7915.13778 (2021) Kivonat